Laboratory of Organometallic Catalysis

A new paper has been published in Journal of Catalysis.

Abstract: A highly efficient and sustainable cobalt(II)-based catalytic system for the regioselective hydroboration of both terminal and internal alkynes is reported. The catalyst, featuring readily accessible N,N,O-donor Schiff-base ligands, is easily synthesised from inexpensive starting materials and operates under solvent-free conditions, proceeding under mild reaction conditions with relatively low catalyst and activator loadings. The developed protocol exhibits excellent β-regioselectivity, enabling the efficient formation of vinylboronate esters across a broad substrate scope that includes aryl-, alkyl-, heteroaryl-, silyl-substituted, as well as internal alkynes. Notably, internal alkynes-substrates that typically require elevated temperatures and prolonged reaction times in cobalt-catalysed hydroboration, are efficiently converted under significantly milder conditions using this system.